The long-term-catheterized urinary tract may offer a particular niche to Providencia stuartii, which is otherwise an uncommon clinical isolate. Biofilm genesis and attachment is favored at pH >8 and can attach directly to a urinary catheter. Many patients with such infections are residents of long-term care facilities. P. stuartii are motile by peritrichous flagella. O'Hara CM, Brenner FW, Miller JM. Causes. P. stuartii has both a fermentative and respiratory metabolism P. stuartii’s resistance to antibiotics also stems from its biofilm formation.
Providencia stuartii is an opportunistic pathogen seen in patients with severe burns or long-term indwelling urinary catheters.
Selection of an empirical agent (while awaiting microbiological identification of the organism and susceptibility testing) should be based on known resistance patterns in the patient's locality (eg, community, hospital, long-term care facility). ESBL-producing multidrug-resistant Providencia stuartii infections in a university hospital. Haynes J, Hawkey PM. Device-associated infections: a macroproblem that starts with microadherence. Jeden studium przypadku zgłaszane przez samego źródła opisano także bakterii jako przyczyny zapalenia wsierdzia (zakażenie serca). Providencia is a genus within the Enterobacteriaceae family closely related to the Providencia and Morganella genera. Gatunek ten jest związany z zapaleniem żołądka i jelit, w większości zgłoszonych przypadków. Ovchinnikova OG, Rozalski A, Liu B, Knirel YA.
Diseases & Conditions
Prawdopodobne P. alcalifaciens gatunek ten jest w równym stopniu związane z zapaleniem żołądka i jelit oraz innych zakażeń przewodu pokarmowego. Warren JW. The outer membrane contains lipopolysaccharides which consist of: lipid A, core polysaccharide, and O antigen in its outer leaflet and phospholipids in the inner leaflet (Salton, 1996. W tym przypadku, P. stuartii jest bardzo inwazyjne, pokazując więcej wytrwałości u kobiet niż u mężczyzn, według badań 1994 zgłoszonych przez eMedicine.
It is of risk group 2 on the P. stuartii has a straight rod morphology and is typically 0.6-0.8 micrometers by 1.5-2.5 micrometers in size P. stuartii is ubiquitous, being commonly found in water, soil, and animal reservoirs It is responsible for many UTIs in patients under long term catheterization and has a high degree of antibiotic resistance, a major concern for hospitals and nursing homes where many patients are vulnerable to infection from this microbe. In laboratory settings,it is best cultured in Nutrient Agar or Columbia agar, with growth best at 37C and a mesophilic temperature range.
Providencia alcalifaciens causes barrier dysfunction and apoptosis in tissue cell culture: potent role of lipopolysaccharides on diarrheagenicity. Consider bladder scanning in cases of suspected neurogenic bladder.Transfer patients if they develop complications that require therapeutic options that the initial treating facility cannot provide (eg, mechanical ventilation, hemodialysis).If a patient is being transferred to another medical institution (eg, skilled nursing facility, long-term care facility) following treatment, convey the nature of the infecting organism to the receiving facility.
Biofilms can also resist high concentration of urea (500mM), calcium and magnesium (up to 50mM) and when presented with these stressors will consolidate.
adcov.com Murata T, Iida T, Shiomi Y, Tagomori K, Akeda Y, Yanagihara I, et al. Medical care of Providencia infection includes initiation of an antimicrobial agent to eradicate infection.
226541-overview 228495-overview These floating communities precede biofilm formation and then coexist with it once a biofilm is created.